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Structure of IBS2 in the talin rod. A, schematic representation of the talin 1974-2293 crystal structure. The upper five-helix bundle is called IBS2-A, and the lower one IBS2-B. The helix numbers shown in brackets are for full-length talin. B, stereo representation of the area located between the two domains in the crystal structure; there is no evidence of hydrophobic or electrostatic interactions between the two domains.
