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. 2008 Dec 4;150(4):1705–1711. doi: 10.1210/en.2008-1316

Figure 5.

Figure 5

Effect of caudal brainstem MC-R blockade [1 μl, SHU9119 (SHU), 4th v delivery] on caudal brainstem leptin receptor stimulation (1 μl, 4th v delivery) on core temperature (A), HR (B), and (C) spontaneous activity in chow-fed rats. Line graphs represent across-rat average parameter measurements through the 8-h recording period. The bracketed time period on the line graph x-axis indicates the periods used in the histograms. The histograms provide 6-h postinjection averages ± sem for each parameter at each dose. *, P < 0.05 (n = 9). ICV, Intracerebroventricular.