Figure 2.

Effect of GLP-1-R blockade on oral preload-induced satiety. After training rats to receive access to a sucrose solution for 15 min at the same time each day, chow intake was measured after either no preload (NP) or an orally consumed sucrose preload (P). Preloads were followed immediately by ip injection of either saline (SAL) or Ex9 (100 μg/kg), after which standard chow was returned to the cage and intake measured over the subsequent 2 h period. Data are mean ± sem. *, P < 0.05.