Table 1.
Metyrapone
|
Hypoglycemia
|
|||||||
---|---|---|---|---|---|---|---|---|
Horse 1 | Horse 2 | Horse 3 | Overall | Horse 1 | Horse 2 | Horse 3 | Overall | |
Slope of ACTH on cortisol | −1.41 | −7.2 | −0.37 | −3.0 | −0.23 | −0.54 | −9.9 | −3.6 |
(0.26) | (2.4) | (1.2) | (0.90) | (0.04) | (0.85) | (3.3) | (1.1) | |
df = 12 | df = 5 | df = 9 | df = 5 | df = 6 | df = 6 | df = 4 | df = 4 | |
(a) | (b) | (NS) | (a) | (a) | (NS) | (b) | (b) | |
Slope of CRH on cortisol | −0.98 | −1.2 | −0.13 | −0.76 | −0.11 | +0.94 | −2.4 | −0.51 |
(0.22) | (0.37) | (0.16) | (0.15) | (0.048) | (0.63) | (1.1) | (0.41) | |
df = 12 | df = 52 | df = 9 | df = 5 | df = 6 | df = 6 | df = 4 | df = 4 | |
(a) | (b) | (NS) | (a) | (b) | (NS) | (b) | (NS) | |
Slope of AVP on cortisol | +0.09 | −5.1 | −0.30 | −1.8 | −0.044 | −0.040 | −0.025 | −0.034 |
(0.25) | (2.2) | (0.90) | (0.81) | (0.015) | (0.027) | (0.011) | (0.011) | |
df = 12 | df = 5 | df = 9 | df = 5 | df = 6 | df = 6 | df = 4 | df = 4 | |
(NS) | (b) | (NS) | (b) | (b) | (NS) | (b) | (b) |
Least-squares linear regression-estimated slopes, in parentheses their se values errors, degrees of freedom (df), and P values (testing that slope is negative against its being nonnegative) for data shown in Fig. 2 (left metyrapone, right hypoglycemia). The overall estimate (fourth and eighth columns) is the average estimate for the three animals. NS, Not significant.
P < 0.01.
P < 0.05.