Table 4.

Relationship Between Change in Insight and Medication Attitude to Change in Psychopathology and Quality of Life

	PANSS Total	PANSS Positive	PANSS Negative	PANSS General	HQOL Total	HSOC	HINPSYC	HINST	HOBACTa	QOLLQOL	Medication compliance	Depressionb
ITAQ	−1.7***	−0.642***	−0.734***	−1.254***	0.117***	0.140***	0.1118***	0.084*	NA	−0.04	0.078***	0.047***
DAI	−3.322***	−1.620***	−0.867***	−1.8***	0.195***	0.159***	0.238***	−0.199***	NA	0.311***	0.235***	−0.108***

Note: Abbreviations are explained in the first footnote to table 3. Days worked is dichotomous (0 = no, 1 = yes). The PANSS negative syndrome scale in this analysis omits 3 items directly reflecting neurocognition and community functioning: “difficulty in abstract thinking,” “passive/apathetic withdrawal,” and “emotional withdrawal.” (1) These analyses adjust for baseline value of the dependent variable as well as of ITQ, DAI, age, LQOLLQOL, neurocognition, depression and HQOL and time of follow-up.

^aThis model did not converge on a stable solution so coefficients and P values could not be calculated.

* P < 0.05, **P < 0.01, ***P < 0.001.

^bCalgary Depression Rating Scale Score.