. 2008 Dec 30;37(4):761–767. doi: 10.1124/dmd.108.025619

TABLE 1.

Kinetics of D2 metabolism in 0.45% cyclodextrin

Values for K_m and k_cat are mean ± S.E. from the hyperbolic curve fitted to the data from a single experiment by least-squares nonlinear regression using KaleidaGraph 3.6 (Synergy Software).

Substrates	K_m	k_cat	k_cat/K_m
	μM	mol/min/mol P450scc	mM^-1 min^-1
Cholesterol	9.1 ± 1.7	6.1 ± 0.4	670
D2	17.5 ± 4.1	2.28 ± 0.20	130
20(OH)D2	12.0 ± 2.3	2.47 ± 0.17	206
17,20(OH)₂D2	18.1 ± 3.2	0.33 ± 0.02	18.2