Table 1.

Extracellular volume fraction, tortuosity, and TMA⁺ loss in the somatosensory neocortex of AQP4^+/+ and AQP4^−/− mice

Genotype	Preparation	α	λ	k′ (s−1)	n
AQP4+/+	In vivo	0.18 ± 0.003	1.61 ± 0.02	0.0031 ± 0.0009	7
AQP4−/−		0.23 ± 0.007*	1.62 ± 0.04	0.0045 ± 0.0001	7
AQP4+/+	In vitro	0.19 ± 0.002	1.61 ± 0.03	0.013 ± 0.001	6
AQP4−/−		0.23 ± 0.003*	1.64 ± 0.01	0.013 ± 0.001	6

Data are expressed as mean ± SEM. n is the number of animals (in vivo) or brain slices (in vitro).

*Statistically significant difference (p < 0.001, two-sample equal-variance t test) between AQP4^+/+ and AQP4^−/−.