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Ultrastructural examination of hybrid glomeruli. Tissue was developed with Bluo-gal, an alternative substrate for β-galactosidase, to mark endothelial cells of host (ROSA26) origin. Host-derived, Bluo-gal positive endothelial cells (En; arrows) and Bluo-gal negative podocytes (Po). In general, GBMs are poorly organized than and podocyte foot processes are absent. RBC: erythrocyte, signifying perfusion. Reproduced with permission (ref. 100).
