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. 2009 Jan-Mar;5(1):306–314. doi: 10.4161/org.8173

Figure 5.

Figure 5

CND remodeling. (A) Left Top: Whole mount E12 Hoxb7-Gfp urogenital tract. Note that Gfp is present in Wolffian duct, ureter and CND but not in the bladder which is invisible in this image Bottom left: A sample of CND epithelium counterstained with E-cadherin showing the multilayered structure, as opposed to the simple tubular structure of the upper segments of Wolffian duct and ureter. Right: Images of Hoxb7-Gfp whole mount urogenital tracts between E11 and E14. Note the expansion of the CND (white dashed arrows at E11, E12 and E13) and its subsequent disappearance (E14, white dashed arrow). (B) Urogenital tracts from E11, E12 and E13 Hoxb7-Gfp embryos counterstained with cytokeratin (red) to illustrate expansion of the CND as the ureter moves into contact with the urogenital sinus. Abbreviations: CND, common nephric duct; ugs, urogenital sinus; Wd, Wolffian duct; ur, ureter.