. Author manuscript; available in PMC: 2009 Oct 28.

Published in final edited form as: J Am Coll Cardiol. 2008 Oct 28;52(18):1468–1481. doi: 10.1016/j.jacc.2008.07.047

Table 2. CHGA 3’-UTR common variant C+87T: Effect of the T allele on blood pressure status and BP values.

Subjects are grouped by absence (C/C) or presence (T/T or C/T) of the T (minor) allele.

2a : CHGA C+87T genotype frequencies and BP status (dichotomize). Results evaluated by chi-square test.

Sex	Genotype	BP-high (n)	BP-low (n)	p (2-sided)
Male	C/C	156	107
	C/T or T/T	95	112	0.004
Female	C/C	112	170
	C/T or T/T	119	148	0.262

2b: CHGA C+87T and BP as a continuous trait. Allelic association (presence or absence of the T allele) evaluated by univariate ANOVA.

Sex	Genotype	SBP (mmHg)	DBP (mmHg)
Male	C/C	137.2+/−1.6	83.7+/−1.3
	C/T or T/T	131.2+/−1.8	77.6+/−1.5
	ANOVA p value	0.016	0.003
Female	C/C	123.8+/−1.7	71.8+/−1.2
	C/T or T/T	126.9+/−1.7	73.8+/−1.3
	ANOVA p value	0.206	0.272