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(A) Normalized curves representing the time-course of NPP development and of Hb consumption applied in this simulation. The half-time and slope values for the NPP and Hb curves shown here were (in h) 24-0.2 and 32-2, respectively. (B and C) As for Figures 2A and 3B respectively. Following Ponder [35], the critical hemolytic volume shown was set at 1.7 times the relative cell volume.
