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. Author manuscript; available in PMC: 2009 Dec 1.
Published in final edited form as: Ann Thorac Surg. 2008 Dec;86(6):1774–1779. doi: 10.1016/j.athoracsur.2008.07.071

Table 1.

Effect of early and late alveolar macrophage products on type 2 pneumocyte response to hypoxia and reoxygenation.

Media
Product Control Media Early AM Mediaa Late AM Mediaa
CINC (pg/mL +/− SD)
Normoxic Control 98 +/− 13 173 +/−8 b 524 +/− 45b, d
Hypoxia
with 15 minutes reoxygenation 259 +/− 21b 2090 +/− 104c 1023 +/− 71c, d
with 4 hours reoxygenation 429 +/− 16b 2445 +/− 342c 2677 +/− 239c
MCP-1 (pg/mL +/− SD)
Normoxic Control 1530 +/− 59 2040 +/− 113b 6475 +/− 250b, d
Hypoxia
with 15 minutes reoxygenation 4075 +/− 217b 16983 +/− 606c 14869 +/− 205c, d
with 4 hours reoxygenation 10639 +/−125b 34350 +/− 2232c 38200 +/− 1716c
a

Cytokine content corrected for baseline content in media;

b

p<0.01 compared with normoxic controls;

c

p<0.01 compared with control media, comparable hypoxia/reoxygenation state;

d

p<0.01 compared with early media, comparable hypoxia/reoxygenation state; CINC=cytokine-induced neutrophil chemoattractant; MCP-1=monocyte chemoattractant protein-1; AM=alveolar macrophage.

N=36 for each media/hypoxia-reoxygenation condition