Table 2.

MT1-MMP target genes

	Accession	Gene	Ranking	HT-MT/HT-siRNA
1	NM_004938	DAPK1	113	2.6
2	NM_182977	NNT	257	2.1
3	NM_005630	SLCO2A1	297	2.2
4	NM_000214	JAG1	444	2.0
5	NM_005026	PI3Kδ	585	2.3
6	NM_000176	NR3C1	640	2.1
7	NM_177560	CK2α	677	2.0
8	NM_139035	SMARCA1	684	3.7
9	NM_007271	STK38	810	2.0
10	NM_198220	SNRPB2	912	2.0
11	NM_001156	ANXA7	944	3.8

NOTE: Ranking of the genes corresponds to the Euclidean distance from the MT1-MMP reference gene, as shown in Supplementary Table S4 that includes approximately 16,000 genes. HT-MT/HT-siRNA, the ratio of gene expression levels in HT-MT cells versus HT-siRNA cells.

Abbreviations: ANXA7, annexin 7; CK2α, protein kinase 2 alpha; DAPK1, death-associated protein kinase 1; JAG1, Jagged 1; NR3C1, nuclear glucocorticoid receptor; NNT, nicotinamide nucleotide transhydrogenase; PI3Kδ, phosphoinositide-3-kinase delta; SLCO2A1, solute carrier organic anion transporter; SMARCA1, actin dependent regulator of chromatin; SNRPB2, small nuclear ribonucleoprotein polypeptide B'; STK38/NDR1, serine-threonine kinase 38/N-myc downstream regulated gene 1.