. Author manuscript; available in PMC: 2010 Jan 1.

Published in final edited form as: Osteoarthritis Cartilage. 2008 Jun 20;17(1):114–123. doi: 10.1016/j.joca.2008.05.006

Table 4.

Phase II construct properties.

Group	WW (mg)	Thickness (mm)	Total Cells (×10⁶)	FI
Control	13.3±1.3	0.45±0.09	5.6±0.5	0.53±0.06
BMP-2	15.0±1.6	0.55±0.06	5.2±0.4	0.76±0.07^a
IGF-I	13.3±3.1	0.55±0.05	5.7±0.9	0.73±0.12^a
TGF-β1	14.5±1.6	0.58±0.05	5.5±0.3	0.72±0.04^a
BMP-2 + IGF-I	16.7±1.3^a	0.59±0.05	5.9±0.4	0.80±0.08^a
BMP-2 + TGF-β1	14.9±1.4	0.57±0.04	5.8±0.6	0.66±0.02^a
IGF-I + TGF-β1	14.2±1.4	0.57±0.06	5.5±0.3	0.59±0.04
BMP-2 + IGF-I + TGF-β1	13.0±1.3	0.53±0.08	6.1±0.4	0.70±0.05

Significantly different from control

Col., total collagen