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. Author manuscript; available in PMC: 2009 Oct 1.
Published in final edited form as: Bioconjug Chem. 2008 Sep 23;19(10):2040–2048. doi: 10.1021/bc800290c

Table 3.

Biodistribution of 111In-1 in PC-3 Tumor Bearing SCID Mice (n = 5).a

Organ/Tissue 0.25-hr PI 0. 5-hr PI 1-hr PI 4-hr PI
Bladder 14.09 ± 21.1 7.03 ± 8.68 1.67 ± 1.06 0.26 ± 0.14
Heart 1.85 ± 0.27 1.00 ± 0.30 0.16 ± 0.06 0.03 ± 0.02
Lung 4.45 ± 0.82 3.56 ± 1.72 1.78 ± 1.64 1.48 ± 2.54
Liver 2.14 ± 0.14 0.88 ± 0.20 0.27 ± 0.07 0.12±0.02
Kidneys 11.84 ± 1.97 5.88 ± 1.91 3.06 ± 0.92 2.24±1.02
Spleen 0.98 ± 0.37 0.59 ± 0.27 0.15 ± 0.08 0.06 ± 0.02
Stomach 1.91 ± 0.29 1.17 ± 0.37 0.34 ± 0.07 0.05 ± 0.03
S. Intestine 3.41 ± 0.54 1.46 ± 0.35 0.62 ± 0.19 0.18 ± 0.11
L. Intestine 1.64 ± 0.29 0.59 ± 0.07 0.54 ± 0.68 0.88 ± 0.39
Muscle 1.00 ± 0.10 0.40 ± 0.13 0.07 ± 0.04 0.02 ± 0.01
Bone 1.21 ± 0.42 0.78 ± 0.40 0.08 ± 0.02 0.05 ± 0.07
Brain 0.17 ± 0.06 0.12 ± 0.04 0.02 ± 0.01 0.00 ± 0.00
Pancreas 14.88 ± 1.86 3.99 ± 0.49 0.96 ± 0.18 0.41 ± 0.14
Tumor#1 7.33 ± 1.18 5.41 ± 1.98 3.91 ± 0.46 2.02 ± 0.34
Tumor#2 6.47 ± 0.82 6.11 ± 1.04 3.52 ± 0.70 2.29 ± 0.36
Blood 4.28 ± 0.59 1.85 ± 0.47 0.33 ± 0.15 0.02 ± 0.02
Carcass 2.26 ± 0.34 1.16 ± 0.41 0.39 ± 0.38 0.05 ± 0.03
Excretion (% ID ± SD) 40.86 ± 4.60 68.70 ± 7.55 89.15 ± 7.11 96.16 ± 1.06
Tumors 6.90 ± 1.06 5.76 ± 1.54 3.72 ± 0.60 2.15 ± 0.36
a

All data, except excretion, are presented as an average % ID/g ± SD.