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. 2009 Apr 3;5(4):e1000347. doi: 10.1371/journal.pcbi.1000347

Table 5. Biological statements extracted from the high-complexity invasion network.

Mutation of interacts via with mutations of genes with GO annotation P
HOG1 Rule 4 invasive growth in response to glucose limitation 0.00027
TEC1 Rule 2 regulation of cellular process 0.00031
STE11 Rule 3 organelle organization and biogenesis 0.00053
HOG1 Rule 4 positive regulation of biological process 0.00064
XBP1 Rule 5 reproduction 0.00070
ROX1 Rule 5 conjugation with cellular fusion 0.0010
HOG1 Rule 4 positive regulation of transcription from RNA polymerase II promoter 0.0011
RAS2 Rule 2 positive regulation of biological process 0.0011
SPO12 Rule 5 reproduction 0.0012
MSN1 Rule 1 cell surface receptor linked signal transduction 0.0014
KSS1 Rule 2 positive regulation of catalytic activity 0.0014
KSS1 Rule 4 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 0.0014
HSL1 Rule 1 cell wall organization and biogenesis 0.0014
HOG1 Rule 4 conjugation with cellular fusion 0.0015
CDC42 Rule 4 positive regulation of metabolic process 0.0015
SRL1 Rule 3 conjugation with cellular fusion 0.0015
MSN1 Rule 1 positive regulation of catalytic activity 0.0018
COD4 Rule 5 reproduction 0.0019
RAS2 Rule 4 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 0.0019
HOG1 Rule 4 response to pheromone 0.0021
HOG1 Rule 4 pheromone-dependent signal transduction during conjugation with cellular fusion 0.0021
RAS2 Rule 2 response to pheromone 0.0022
GLN3 Rule 2 protein targeting 0.0023
KSS1 Rule 2 intracellular signaling cascade 0.0023
URE2 Rule 3 reproduction 0.0025
URE2 Rule 3 response to pheromone 0.0025
YPS1 Rule 3 G-protein coupled receptor protein signaling pathway 0.0025
KTR2 Rule 3 G-protein coupled receptor protein signaling pathway 0.0025
TEC1 Rule 2 positive regulation of biological process 0.0025
DIG2 Rule 2 osmosensory signaling pathway 0.0027
PBS2 Rule 4 replicative cell aging 0.0031
XBP1 Rule 5 cell communication 0.0031
XBP1 Rule 5 response to chemical stimulus 0.0031
CDC42 Rule 4 regulation of transcription, DNA-dependent 0.0032
YPS1 Rule 3 filamentous growth 0.0038
STE12 Rule 4 positive regulation of metabolic process 0.0038
STE20 Rule 4 positive regulation of metabolic process 0.0038
DSE1 Rule 5 cellular component organization and biogenesis 0.0039
TEC1 Rule 4 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 0.0039
HSL1 Rule 5 pheromone-dependent signal transduction during conjugation with cellular fusion 0.0040
STE12 Rule 3 cell wall organization and biogenesis 0.0040
STE20 Rule 3 cell wall organization and biogenesis 0.0040
PRY2 Rule 2 osmosensory signaling pathway 0.0041
IPK1 Rule 4 invasive growth in response to glucose limitation 0.0043
KSS1 Rule 2 protein amino acid phosphorylation 0.0043
YPL114W Rule 5 developmental process 0.0045
HOG1 Rule 5 protein targeting 0.0048
PDE2 Rule 3 intracellular signaling cascade 0.0048
DIG2 Rule 2 response to chemical stimulus 0.0048
ROX1 Rule 5 response to pheromone during conjugation with cellular fusion 0.0048
TPK1 Rule 2 cell surface receptor linked signal transduction 0.0049
YJL017W Rule 5 establishment of cell polarity 0.0049
YJL017W Rule 1 positive regulation of catalytic activity 0.0049
MIH1 Rule 5 cell communication 0.0051
STE20 Rule 2 growth 0.0052
RSR1 Rule 1 sporulation 0.0054
STE20 Rule 2 filamentous growth 0.0055
MSN1 Rule 2 M phase of mitotic cell cycle 0.0055
MSN1 Rule 2 conjugation with cellular fusion 0.0055
RSR1 Rule 3 cellular metabolic process 0.0057
DBR1 Rule 2 mitotic cell cycle 0.0059
TEC1 Rule 4 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 0.0060
MSN1 Rule 2 invasive growth in response to glucose limitation 0.0062
SRL1 Rule 3 response to pheromone during conjugation with cellular fusion 0.0065
MSN1 Rule 3 cell communication 0.0068
TEC1 Rule 2 positive regulation of metabolic process 0.0071
CTS1 Rule 2 osmosensory signaling pathway 0.0071
PHD1 Rule 5 protein localization 0.0073
RIM13 Rule 5 conjugation with cellular fusion 0.0076
RIM13 Rule 5 invasive growth in response to glucose limitation 0.0076
CLN3 Rule 3 response to pheromone 0.0076
DIA3 Rule 5 response to pheromone 0.0076
BUD4 Rule 1 regulation of molecular function 0.0077
IME2 Rule 3 G-protein coupled receptor protein signaling pathway 0.0077
PAM1 Rule 3 cell morphogenesis 0.0077
KSS1 Rule 1 biopolymer metabolic process 0.0081
GPR1 Rule 1 response to pheromone 0.0082
BEM1 Rule 1 nitrogen utilization 0.0085
STE12 Rule 1 intracellular signaling cascade 0.0087
STE12 Rule 3 nitrogen utilization 0.0090
IPK1 Rule 4 conjugation with cellular fusion 0.0090
CDC42 Rule 3 cell wall organization and biogenesis 0.0090
URE2 Rule 3 signal transduction 0.0090
YPS1 Rule 3 reproduction 0.0090
YPS1 Rule 3 invasive growth in response to glucose limitation 0.0090
YPS1 Rule 3 pseudohyphal growth 0.0090
KTR2 Rule 3 reproduction 0.0090
MSN1 Rule 1 G-protein coupled receptor protein signaling pathway 0.0092
RSR1 Rule 3 cellular macromolecule metabolic process 0.0093
CDC42 Rule 4 regulation of transcription from RNA polymerase II promoter 0.0093
FLO8 Rule 5 filamentous growth 0.0094
GLN3 Rule 2 macromolecule metabolic process 0.0095
IPK1 Rule 3 cell communication 0.0095