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. 2009 Apr 2;4(4):e5011. doi: 10.1371/journal.pone.0005011

Figure 3. Changes of CDKN1C expression in response to DZNep, TSA, Aza and their combinations.

Figure 3

(A) SK-BR-3, BT-474, MDA-MB-231 and MCF10A cells were treated with 5 µM DZNep (D), 100 nM TSA (T), and 5 uM 5-AzaC (A) along or in indicated combinations. Expression of CDKN members were analyzed by quantitative RT-PCR. Shown were the folds of induction relative to the untreated cells. (B) Western blot analysis of CDKN1C protein expression in SK-BR-3 and BT-474 cells. (C) RT-PCR results show no change of LIT1 expression upon indicated drug treatment. .