Table 6.

Factors Predicting the Discrepancy^a of Patient-Assessed Disease Outcome (PGI-I) Versus Physician-Assessed Disease Outcome (CGI-I) at Week 8^b

Predictor of Discrepancy	t Values	p Values
Low discrepancy between CGI-I and PGI-I
Low decrease in MADRS depression severity	–5.68	<.0001
Low decrease in BPI-SF pain interference with other people	–2.57	=.0106
Low decrease in SCL-90-R interpersonal sensitivity	–2.49	=.0135
High discrepancy between CGI-I and PGI-I
Low decrease in BPI-SF average pain	2.37	=.0186
Low decrease in SCL-90-R patient-rated depression	3.55	=.0005

^aDiscrepancy is defined as PGI-I score minus CGI-I score at week 8.

^bCovariates included in the regression were the change from baseline to week 8 in number of pains, BPI-SF average pain, MADRS total score, BPI-SF interference (all items), and SCL-90-R (all items); gender; and age.

Abbreviations: BPI-SF = Brief Pain Inventory-Short Form, CGI-I = Clinical Global Impressions-Improvement scale, MADRS = Montgomery-Asberg Depression Rating Scale, PGI-I = Patient Global Impression of Improvement, SCL-90-R = Symptom Checklist-90-Revised.