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Control mice and HIF-1α-deficient mice were subjected to bile duct ligation or sham operation. Fourteen days later, levels of type I collagen were quantified in the liver by real-time PCR. aSignificantly different from sham-operated mice (P < 0.05). bSignificantly different from control mice subjected to bile duct ligation (P < 0.05). Data are expressed as means ± SE; n = 6.
