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A: plasma ALT activities were measured 6 h after intraperitoneal administration of 0.15 or 0.10 mmol/kg DQ and, in addition, 5% DMSO/PBS (vehicle) or 10 mg/kg of the JNK inhibitor SP-600125. Data represent means ± SE of n = 4–6 animals per group. B: Western blot analysis of c-Jun and p-c-Jun (indicator of JNK) before and 6 h after treatment with DQ and SP-600125.
