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Bile flow (A), the biliary efflux of GSSG and GSH + GSSG (B), and plasma GSH and GSSG concentrations (C) were measured before and after intravenous administration of 150 mg/kg menadione at t = 0 min (arrow). Data represent means ± SE of n = 6 animals. *P < 0.05 (compared with baseline, t = 0).
