Fig. 5.
Suppression of cisplatin-induced necrosis in Ctr1 knockdown cells. HEK293 cells transfected with control or Ctr1 siRNA were treated with 150 μM cisplatin for 8 h, and necrosis was measured by propidium iodide (PI) staining (A) and LDH assay (B). Values are means ± SD; n = 3. *Statistically significant difference from the untreated group (P < 0.05). #Statistically significant difference from the control siRNA treated group (P < 0.05).