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Transfection with siIGFBP-3 prevents hypoxic HPASMC proliferation. Cells were incubated in 1% or 21% O2. Cell counts were performed at 72 h. *P < 0.001, 1% O2 vs. 21% O2; †P < 0.001, hypoxic cells transfected with siIGFBP-3 vs. hypoxic control cells.
