Table 1.

Effect of physical activity and regulated energy on final body weight and the carcinogenic response in the mammary gland

Treatment	Carcinogenic Response			Final Body Weight, g	Total Food Intake, g
	Incidence, %	Multiplicity, number per rat	Latency, days
Sedentary control	92.6	3.44±0.47	41 (38, 44)	215±3.6	635±11
Regulated energy	77.8*	2.11±0.38*	46 (43, 49)*	197±3.5*	532±8*
Physically active	66.7*	1.62±0.31*	45 (42, 47)*	199±3.5*	569±10*†
Overall P value	0.06	0.006	0.022	<0.001	<0.001

Final body weight values are expressed as means ± SE. Carcinogenic response values are expressed as percentages for cancer incidence, as means ± SE (n =27/group) for cancer multiplicity, and as mean time to first palpable mammary tumor histologically confirmed to be an adenocarcinoma (with 95% confidence intervals) for cancer latency.

^*P < 0.05 compared with sedentary control.

^†P < 0.05 compared with regulated energy.