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. 2009 Jan 8;106(3):880–886. doi: 10.1152/japplphysiol.91292.2008

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Copyright © 2009, American Physiological Society

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Fig. 1. — A: experimental setup. Each subject breathed through a face mask attached to a low-resistance 1-way valve with a built-in hot-wire flowmeter. Valve mechanism allowed subjects to inspire room air or a selected gas mixture from a 200-liter Douglas bag. TCD, transcranial Doppler; , end-tidal Pco₂; , end-tidal Po₂; V̇e, minute ventilation; Vt, tidal volume. B: experimental protocol. CO₂ was administered to each subject at rest (i) and during exercise (ii). Order of the rest and exercise trials was randomized for each subject. V̇o₂, O₂ uptake.

Inline graphic — A: experimental setup. Each subject breathed through a face mask attached to a low-resistance 1-way valve with a built-in hot-wire flowmeter. Valve mechanism allowed subjects to inspire room air or a selected gas mixture from a 200-liter Douglas bag. TCD, transcranial Doppler; , end-tidal Pco₂; , end-tidal Po₂; V̇e, minute ventilation; Vt, tidal volume. B: experimental protocol. CO₂ was administered to each subject at rest (i) and during exercise (ii). Order of the rest and exercise trials was randomized for each subject. V̇o₂, O₂ uptake.