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. 2008 Dec 24;296(3):C476–C488. doi: 10.1152/ajpcell.00456.2008

Fig. 2.

Fig. 2.

Galgt2 transgenic WT and mdx muscles are protected from loss of force during eccentric contractions. A: 5-mo-old WT, Galgt2WT, mdx, and Galgt2mdx muscles were compared for force drop during repetitive eccentric contractions. Galgt2WT and Galgt2mdx were both significantly changed relative to either WT or mdx. B: 2-mo-old and 5-mo-old Galgt2WT and Galgt2mdx muscles were compared for force drop during eccentric contractions. C: 2-mo-old Galgt2WT and Galgt2mdx muscles were compared with 3-wk-old (3wk) WT and mdx muscles. The 3-wk-old WT and mdx muscles are as small or smaller in cross-sectional area than 2-mo-old Galgt2WT and Galgt2mdx muscles. P < 0.001 for Galgt2WT 5mo or Galgt2mdx 5mo compared with either WT 5mo or mdx 5mo (in A) and for Galgt2WT 2mo or Galgt2mdx 2mo compared with either WT 3wk or mdx 3wk (in C). Errors are SE for n = 7 (WT 5mo), 8 (Galgt2WT 5mo), 4 (mdx 5mo), 5 (Galgt2mdx 5mo), 3 (Galgt2WT 2mo), 10 (Galgt2mdx 2mo), 2 (WT 3wk), and 6 (mdx 3wk) muscles.