Table 1.
Effects of diesel exposure on heart rate, blood pressure and markers of arterial stiffness
|
Air (n = 12) |
Diesel exhaust (n = 12) |
Significance | |||||
| Time, mins | +10 | +20 | +30 | +10 | +20 | +30 | - |
| Heart rate, bpm | 57 ± 2 | 55 ± 2 | 55 ± 2 | 57 ± 2 | 55 ± 2 | 54 ± 2 | P = 0.66 |
| Systolic BP, mmHg | 118 ± 2 | 114 ± 2 | 115 ± 3 | 114 ± 2 | 114 ± 2 | 115 ± 3 | P = 0.26 |
| Diastolic BP, mmHg | 67 ± 2 | 65 ± 2 | 66 ± 2 | 65 ± 2 | 68 ± 2 | 67 ± 3 | P = 0.48 |
| MAP, mmHg | 80 ± 2 | 78 ± 2 | 79 ± 2 | 79 ± 2 | 81 ± 3 | 81 ± 3 | P = 0.57 |
| Augmentation pressure, mmHg | -2.3 ± 0.7 | -2.2 ± 0.8 | -2.5 ± 0.7 | 0.2 ± 0.9 | -1.3 ± 0.9 | -1.8 ± 0.8 | P = 0.01 |
| Augmentation index, % | -7.0 ± 2.3 | -7.4 ± 2.6 | -7.9 ± 2.2 | 0.8 ± 3.2 | -3.8 ± 3.5 | -5.8 ± 2.7 | P = 0.02 |
| Time to wave reflection, ms | 187 ± 8 | 189 ± 11 | 180 ± 7 | 171 ± 11 | 163 ± 9 | 180 ± 8 | P = 0.03 |
Values are Mean ± SEM;
diesel exhaust versus filtered air (repeated measures ANOVA)
BP = blood pressure; MAP = mean arterial pressure