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. 1993 Oct;31(10):2824–2827. doi: 10.1128/jcm.31.10.2824-2827.1993

Cytomegalovirus antigenemia: clinical correlations in transplant recipients and in persons with AIDS.

T Mazzulli 1, R H Rubin 1, M J Ferraro 1, R T D'Aquila 1, S A Doveikis 1, B R Smith 1, T H The 1, M S Hirsch 1
PMCID: PMC266028  PMID: 8253997

Abstract

We evaluated a rapid immunoperoxidase technique for the detection of cytomegalovirus (CMV) antigenemia in peripheral blood neutrophils of 56 transplant recipients (117 specimens) and 36 persons with AIDS (59 specimens). Antigenemia was 92% sensitive and 98% specific for the detection of clinical CMV infection in transplant recipients and 100% sensitive and 86% specific in persons with AIDS. Overall, CMV antigenemia was a more rapid and sensitive method for the detection of clinical CMV infection than either shell vial culture or conventional tube culture of blood.

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Selected References

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