Table 5.

Association of CRP haplotypes with COPD and ln(CRP)

	COPD*		Ln(CRP) †
Haplotype	OR (95%CI)	P-value	Coefficient ± SE	P-value
H1	0.85 (0.57–1.27)	0.42	-0.33 ± 0.13	0.01
H2	0.86 (0.64–1.16)	0.43	-0.13 ± 0.13	0.34
H3	1.64 (0.83–3.27)	0.16	-0.58 ± 0.20	0.004
H4	REFERENT		REFERENT
H5	1.35 (0.69–2.65)	0.38	-0.02 ± 0.21	0.92
Others‡	2.91 (0.77–0.98)	0.12	0.66 ± 0.27	0.01

* Logistic regression analyses were adjusted for age, sex and tobacco consumption (pack-years smoked).

† Linear regression analyses were adjusted for age, sex, BMI and 6MWD.

‡ Rare haplotypes (frequency < 2.5%) were coded in aggregate as "others"