Table 2.
Human Trials comparing endomyocardial biopsy and CMR in the diagnosis of acute heart transplant rejection
| Author | Year | n | Scans | Positive biopsies | Age | Time from Txplant | Delay to CMR | Histologic Grading |
| Almenar L | 2003 | 40 | 64 | - | 51 +/- 13 yrs | 13–3725 days | - | Defined* |
| Marie P.Y | 2001 | 68 | 123 | 19 | 51 +/- 13 yrs | 8 +/- 11 mth | <4 days | ISHLT[47] |
| Marie P.Y | 1998 | 52 | 52 | 9 | 51 +/- 14 yrs | 32 +/- 42 mth | < 1 wk | ISHLT[47] |
| Smart F.W. | 1993 | 8 | 33 | 3 | - | 1–7 mth | <24 hrs | McAlister[48] |
| Mousseaux E | 1993 | 39 | 39 | 7 | 52 (18–69) yrs | 7 d–5 yrs | <48 hrs | ISHLT[47] |
| Revel | 1989 | 29 | 33 | 8† | 45 (11–60) yrs | 3 wk-5 yrs | <3 days | Billingham[46] |
| Lund G | 1988 | 9 | 35 | 2 | 5 mos – 59 yrs | 1–13 wks | <24 hrs | Not stated |
| Wisenberg G | 1987 | 25 | 62 | 16 | 14–57 yrs | 9–107 days | <24 hrs | Defined‡ |
| Totals | 302 | 521 | 75 | |||||
- Not available
* ≥1 focus of myocyte necrosis
† rejection defined as Billingham grade 1 or greater
‡ lymphocytic infiltrate with myocytolysis