Table 3.

Severe malaria and TLR9 genotype-based association analysis

		The Gambia1				Malawi2
Case-control	genotypes	OR	95% CI		p-value	OR	95% CI		p-value
rs187084	CT vs TT	0.96	0.75	1.23	0.79	0.82	0.62	1.09	0.17
	CC v TT	0.98	0.57	1.70	0.97	0.60	0.35	1.02	0.06
rs5743836	CT vs TT	0.98	0.74	1.30	0.90	1.01	0.75	1.34	0.95
	CC vs TT	0.81	0.56	1.15	0.25	0.63	0.42	0.97	0.04
rs352139	AG vs GG	1.01	0.77	1.30	0.97	1.22	0.91	1.63	0.17
	AA vs GG	1.22	0.85	1.74	0.27	1.43	0.98	2.07	0.06
rs352140	TC vs CC	0.97	0.76	1.24	0.84	0.77	0.59	1.01	0.06
	TT vs CC	1.36	0.82	2.26	0.22	0.78	0.49	1.25	0.31

¹Adjusted for HbS and ethnicity

² Adjusted for HbS