Skip to main content
. Author manuscript; available in PMC: 2010 Apr 1.
Published in final edited form as: Mitochondrion. 2008 Dec 11;9(2):86–95. doi: 10.1016/j.mito.2008.12.001

Fig. 4. Morphometry of mitochondria in mouse embryonic stem cells (SC) and differentiatedcardiomyocytes (CM).

Fig. 4

Control cells and tafazzin-deficient cells (ΔTAZ) were analyzed. A, Average size of mitochondrial cross sections. B, Proportion of mitochondria with tubular (T), lamellar (L), and mixed (L/T) cristae morphology. C, Proportion of mitochondria with abnormal cristae. Embryonic stem cells contain mainly tubular mitochondria that are not altered by tafazzin deletion. Differentiated cardiomyocytes contain mainly lamellar mitochondria that show significant abnormalities in the absence of tafazzin. Data are means with s.e.m. of two experiments, in each of which we evaluated hundred mitochondrial cross sections. *Significant difference between control SC and control CM (p<0.01); **Significant difference between control CM and ΔTAZ CM (p<0.05).