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. Author manuscript; available in PMC: 2009 Mar 25.
Published in final edited form as: Annu Rev Biophys Biomol Struct. 2007;36:79–105. doi: 10.1146/annurev.biophys.34.040204.144521

Figure 1.

Figure 1

Changing macromolecular interactions by changing the solvent environment. The “solvent continuum.” Biological macromolecules can form miniphases that have stable insides and outsides. Small molecules can only form mixed solutions or separate phases (see text).