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. Author manuscript; available in PMC: 2009 Apr 1.
Published in final edited form as: Dig Dis Sci. 2007 Dec 4;53(4):997–1012. doi: 10.1007/s10620-007-0133-6

Figure 3. Inhibition of TNFα-induced activation of NFκB by ABC294640.

Figure 3

Fibroblasts transfected with a TNFα-responsive promoter linked to luciferase were treated with the indicated concentrations of ABC294640 and then treated with TNFα for 6 hr. The amount of luciferase expressed by the cells was then measured by luminescence. Values represent the mean ± sd luciferase activity in triplicate samples in a typical experiment, each experiment was performed twice.