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. 2009 Apr 10;5(4):e1000383. doi: 10.1371/journal.ppat.1000383

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Sturm et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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(A) SPR analysis of OAT with Trx. The experimental setup was chosen as described in the Figure 2 caption. A strong and specific interaction can be observed with the C33S mutant, whereas wild type Trx and the double mutant C30S/C33S show hardly any interaction. (B) Specific activity of PfOAT in the presence of equimolar concentrations of Trx, TrxC33S, and TrxC30S/C33S.