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. 2009 Apr 2;4(4):e5147. doi: 10.1371/journal.pone.0005147

Figure 1. J8-specific serum IgG antibody response in BALB/c mice immunized parenterally with J8-DT or DT.

Figure 1

Cohorts of BALB/c mice (n = 10/group) received a primary immunization on day 0 followed by three boosts on day 21, 28 and 35. Serum samples were collected before each vaccination and one week after last boost. The geometric mean titres (GMT) of J8-specific serum IgG (a) and mean concentrations of various J8-specific IgG isotypes in the final bleed serum of BALB/c mice (b), determined by ELISA are shown.