Table 1. Expected Mendelian distribution in Glu-Cre;Vhl colony.
Glu-Cre positive offspring | ||||||
strain | Cre;Vhl +/+ | Cre;Vhl f/+ | Cre;Vhl f/f | N | χ2 | p-value |
A/J | 30.6% | 46.9% | 22.4% | 49 | 0.837 | 0.658 |
C57BL/6 | 29.1% | 40.5% | 30.4% | 79 | 2.873 | 0.238 |
Mendelian % | 25.0% | 50.0% | 25.0% |
Glu-Cre;Vhl f/+ mice were intercrossed and the genotypes of their offspring determined for each background strain at time of weaning.