Table 2. Expected Mendelian distribution in Rip-Cre;Vhl colony.
Rip-Cre positive offspring | ||||||
strain | Cre;Vhl +/+ | Cre;Vhl f/+ | Cre;Vhl f/f | N | χ2 | p-value |
A/J | 29.3% | 56.0% | 14.7% | 75 | 4.307 | 0.116 |
C57BL/6 | 28.9% | 53.9% | 17.1% | 76 | 2.605 | 0.272 |
Balb/C | 30.4% | 53.6% | 16.1% | 56 | 2.571 | 0.276 |
Mendelian % | 25.0% | 50.0% | 25.0% |
Rip-Cre;Vhl f/+ mice were intercrossed and the genotypes of their offspring determined for each background strain at time of weaning.