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. 2009 Apr 2;4(4):e4897. doi: 10.1371/journal.pone.0004897

Table 2. Expected Mendelian distribution in Rip-Cre;Vhl colony.

Rip-Cre positive offspring
strain Cre;Vhl +/+ Cre;Vhl f/+ Cre;Vhl f/f N χ2 p-value
A/J 29.3% 56.0% 14.7% 75 4.307 0.116
C57BL/6 28.9% 53.9% 17.1% 76 2.605 0.272
Balb/C 30.4% 53.6% 16.1% 56 2.571 0.276
Mendelian % 25.0% 50.0% 25.0%

Rip-Cre;Vhl f/+ mice were intercrossed and the genotypes of their offspring determined for each background strain at time of weaning.