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. Author manuscript; available in PMC: 2009 Mar 25.
Published in final edited form as: J Comput Biol. 2008 Apr;15(3):231–240. doi: 10.1089/cmb.2007.0178

Table 1.

List of 21 P. falciparum proteins whose structures were analyzed for the presence of druggable pockets. The resolution of the structures ranged from 1.1 to 3.0 Å.

Protein Abbreviated Name PDB ID Resolution (Å)
acyl-CoA binding protein ACBP 1hbk 2.00
fructose-1,6-bisphosphate aldolase ALDO 1a5c 3.00
adenylosuccinate synthetase AdSS 1p9b 2.00
cyclophilin CyP 1qng 2.10
dihydrofolate reductase-thymidylate synthase DHFR-TS 1j3i 2.33
enoyl-acyl carrier protein reductase ENR 1vrw 2.35
ferredoxin Fd 1iue 1.70
glutathione reductase GR 1onf 2.60
glutathione S-transferase GST 1q4j 2.20
hypoxanthine-guanine-xanthine phosphoribosyltransferase HGXPRT 1cjb 2.00
kinesin KinI 1ry6 1.60
L-lactate dehydrogenase LDH 1t24 1.70
peptide deformylase PDF 1rl4 2.18
gamete antigen 27 Pfg27 1n81 2.10
phosphoglcerate kinase PGK 1ltk 3.00
protein kinase 5 PK5 1v0o 1.90
plasmepsin II PM2 1lf2 1.80
purine nucleoside phosphorylase PNP 1nw4 2.20
Rab6 Rab6 1d5c 2.30
triosephosphate isomerase TIM 1o5x 1.10
thioredoxin Trx 1syr 2.95