TABLE 2.
Results of caspase 3 biochemical assays
Treatment group
|
Caspase 3 activity (fluorescence intensity/mg protein)
|
|
---|---|---|
Relative value | Absolute value | |
4 h ischemia, 24 h reperfusion (n=6 hearts) | 0.77 ± 0.80 | 32.45 ± 29.16 |
24 h ischemia (n=6 hearts) | 1.06 ± 0.80 | 35.61 ± 26.72 |
Controls without ischemia (n=7 hearts) | 1.00 ± 0.89 | 33.50 ± 29.76 |
Thymuses from mice given dexamethasone (n=6) | 9.04 ± 3.32* | 1071 ± 393* |
Thymuses from mice given saline (n=6) | 1.0 ± 0.46 | 118.50 ± 54.33 |
Results are means ± sd of ratios of intensity of fluorescence relative to that in normal hearts or to that in thymuses from mice given saline. Absolute values are shown as well.
P = 0.0040 compared with results in thymuses from mice given saline.