TABLE 3.
Treatment group
|
Caspase 8 activity (fluorescence intensity/mg protein)
|
|
---|---|---|
Relative value | Absolute value | |
4 h ischemia, 24 h reperfusion (n=6 hearts) | 0.33 ± 0.60 | 27.64 ± 49.90 |
24 h ischemia (n=6 hearts) | 0.82 ± 0.65 | 68.42 ± 53.85 |
Controls without ischemia (n=7 hearts) | 1.0 ± 0.96 | 83.04 ± 79.65 |
Thymuses from mice given dexamethasone (n=6) | 6.87 ± 3.05* | 7811 ± 3469* |
Thymuses from mice given saline (n=6) | 1.0 ± 0.30 | 1134 ± 339 |
Results are means ± sd of ratios of intensity of fluorescence relative to that in normal hearts or thymuses from mice given saline. Absolute values are shown as well.
P = 0.0039 compared with results in thymuses from mice given saline.