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Modifier screens: A modifier screen is conducted in order to find genes that play a role in a process of interest. Random mutations created by mutagenesis or selected mutants already suspected to be involved in the pathway investigated as well as collections of Enhancer-Promoter (EP)-elements and RNAi stocks may be used to identify genes able to modify (enhance or suppress) the phenotype. In this figure suppression and enhancement of an eye phenotype is illustrated.
