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. 2009 Feb 23;10(2):674–701. doi: 10.3390/ijms10020674

Table 4.

Alterations in mtDNA content of human cancers.

Cancer type
Case number
Alterations in mtDNA content
Reference
Increase or Decrease Frequency (%)
Breast cancer
  N = 25 Decrease 80 [76]
  N = 60 Decrease 63 [26]
  N = 59
Decrease
78
[27]

Gastric cancer
  N = 31
Decrease
55
[35]

Hepatocellular carcinoma
  N = 38 Decrease 61 [39]
  N = 31
Decrease
77
[77]

Renal cancer
  N = 13 Decrease 61 [78]
  N = 37
Decrease
91
[79]

Colorectal cancer
  N = 25 Increase 40 [29]
  N = 153
Increase
39
[80]

Lung cancer
  N = 31
Increase
48
[29]

Papillary thyroid cancer
  N = 20
Increase
65
[76]

Prostate cancer
  N = 9 Increase 78 [81]