Skip to main content
. 2009 Feb 1;10(2):395–406. doi: 10.3390/ijms10020395

Table 1.

Grades of damage determined in the hepatocytes of mice treated with α-mannan (Man), and with aflatoxin B1 (AFB1).

Agent/dose Time (h) Grades of damage (%)

G0 G1 G2 G3
Corn oil
0.02 mL
4 84 13 2 1
10 87 11 2 0
16 92 4 3 1

DMSO
0.02 mL
4 77 17 4 2
10 87 5 4 4
16 86 8 4 2

Man
700 mg/kg
4 91 7 2 0
10 85 10 3 2
16 89 6 3 2
AFB1 1.0 mg/kg 4 72 12 8 8
10 2 9 24 65
16 18 18 27 37

Man + AFB1
100 + 1.0 mg/kg
4 67 8 10 15
10 4 10 29 57
16 16 20 30 34

Man + AFB1
400 + 1.0 mg/kg
4 75 12 8 5
10 23 20 23 35
16 32 15 25 28

Man + AFB1
700 + 1.0 mg/kg
4 80 14 3 3
10 42 18 17 23
16 36 28 19 17

Data were obtained from 100 nuclei/mouse (5 mice per group).