. Author manuscript; available in PMC: 2009 Mar 25.

Published in final edited form as: Antioxid Redox Signal. 2008 Feb;10(2):355–370. doi: 10.1089/ars.2007.1916

Table 3.

Protective Antioxidants in Animal Models of Lung Fibrosis

Fibrogenic agent	Catalytic antioxidants	Antioxidant scavengers
Bleomycin	SOD, catalase, MnTBAP	Vitamin E, NAC, erdosteine, amifostine, U-74389, curcumin, ginko biloba
Paraquat	SOD, MnTBAP, PBN, TEMPOL	Vitamin E, GSH, NAC, erdosteine, curcumin
Amiodarone	PBN	Vitamin E, NAC, BHA, curcumin
Radiation	SOD, catalase, AEOL 10113, AEOL 10150, EUK 189	Vitamin E, NAC, amifostine, curcumin, ginko biloba
TGF-β	Unknown	Unknown
Silica	Catalase, MnTBAP, TEMPO	GSH, NAC, U-75412, U-74389
Asbestos	SOD, catalase, TEMPO	NAC