Table 1.

Baseline clinical characteristics of eligible patients

Baseline characteristics	n	%
Patients eligible/enrolled	31/33	94
Age at enrollment, years
Mean	61.0
Median	61.0
Range	39–77
Race/ethnicity
Hispanic	12	39
White	11	36
Black	6	19
Asian	2	6
ECOG performance status
0	16	52
1	14	45
2	1	3
Sites of metastatic disease
Nonvisceral only	9	29
Visceral (liver, lung, adrenal) only	7	23
Both	15	48
No. of metastatic sites
One	15	48
Two	10	32
Three or more	6	19
Prior adjuvant therapy
Adjuvant ET	21	68
Adjuvant chemotherapy	15	48
Surgery	22	71
Radiation	16	52
Prior metastatic therapya
Not ET resistant (no prior ET or ET sensitiveb)	9	29
ET resistant	22	71
Tamoxifen	1	5
Aromatase inhibitors	21	95
One prior ET	12	57
Two prior ETs	7	33
Three prior ETs	2	10

^aOne hundred percentage is calculated for each subgroup.

^bPatient #23 had complete remission to prior ET and a relapse interval of 2 years.

ECOG, Eastern Cooperative Oncology Group; ET, endocrine therapy.