Table 2. Effect of LPS and resistin on the expression of key insulin-responsive genes.

Animals and treatments are described under Materials and Methods. Real-time RT-PCR was performed as described under Materials and Methods, and results were normalized to (β-actin. Data are means ± S.E.M. (n = 4–6) and are reported as -fold of control values.

	1 h after Injection			8 h after Injection			24 h after Injection
	R	LPS	R + LPS	R	LPS	R + LPS	R	LPS	R + LPS
GLUT-4	0.9 ± 0.2	0.7 ± 0.3	1.0 ± 0.2	2.3 ± 1.0	0.3 ± 0.2a	0.2 ± 0.1a	1.0 ± 0.1	0.2 ± 0.04a	0.2 ± 0.03a
GK	0.6 ± 0.1	1.2 ± 0.5	2.6 ± 0.6ab	0.7 ± 0.2	0.03 ± 0.01a	0.04 ± 0.01a	0.6 ± 0.06	0.1 ± 0.03a	0.1 ± 0.02a
PCK-1	0.8 ± 0.2	2.6 ± 0.7a	2.8 ± 0.7a	1.1 ± 0.2	0.3 ± 0.1a	0.5 ± 0.1a	0.5 ± 0.1	1.7 ± 0.3a	1.8 ± 0.7a
G6Pase	1.3 ± 0.2	2.3 ± 0.6a	1.3 ± 0.5	0.9 ± 0.3	0.02 ± 0.01a	0.04 ± 0.1a	1.6 ± 0.5	0.4 ± 0.1a	0.3 ± 0.07a

R, resistin.

^ap < 0.05 compared with the absence of LPS.

^bp < 0.05 compared with the absence of resistin.