Table 3.

Relationship between RBC Hb–O₂ P₅₀ and Hb modulators, Hb isoforms, RBC pHi and Hill coefficients of sculpins using conventional and PIC correlations.

	conventional			PIC
parameter	m	r2	p-value	m	r2	p-value
ATP/Hb	−3.58	0.06	0.46	1.43	<0.01	0.83
GTP/Hb	0.02	0.08	0.41	3.80	0.04	0.54
total Hb isoforms	−0.01	<0.01	0.99	−0.83	0.04	0.54
anodic Hb isoforms	−0.18	<0.01	0.92	−1.35	0.07	0.43
cathodic Hb isoforms	0.43	<0.01	0.88	−0.02	<0.01	0.99
RBC pHi	62.14	0.12	0.32	48.05	0.09	0.40
n (whole)	−38.79	0.25	0.11	−0.01	0.17	0.21
n (stripped)	−16.89	0.09	0.37	−0.01	0.03	0.61
n (reconstituted)	−7.24	0.01	0.76	−0.01	0.02	0.67