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. 2008 Dec 4;8:359. doi: 10.1186/1471-2407-8-359

Table 2.

Genotyping frequencies for HER-2 in cases and controls and their association with risk of overall lung cancer

Genotype Case
(n = 407)
Control
(n = 407)
asOR (95% CI)a p-value
-3444 C>T CC 141 140 1
CT 201 205 0.97 (0.72 – 1.32) 0.86
TT 65 62 1.04 (0.68 – 1.58) 0.85
CT+TT 266 267 0.99 (0.74 – 1.32) 0.94

CC+CT 342 345 1
TT 65 62 1.06 (0.72 – 1.55) 0.77

-1985 G>T GG 144 140 1
GT 196 205 0.93 (0.69 – 1.26) 0.64
TT 67 62 1.05 (0.69 – 1.59) 0.82
GT+TT 263 267 0.96 (0.72, 1.28) 0.77

GG+GT 340 345 1
TT 67 62 1.10 (0.75-1.60) 0.63

I655V A>G AA 304 300 1
AG 97 97 0.99 (0.71 – 1.36) 0.93
GG 5 6 0.82 (0.25 – 2.72) 0.75
AG+GG 102 103 0.98 (0.71 – 1.34) 0.88

AA+AG 401 397 1
GG 5 6 0.83 (0.25 – 2.73) 0.75

P1170A C>G CC 144 137 1
CG 199 206 0.92 (0.68 – 1.25) 0.59
GG 64 64 0.95 (0.63 – 1.45) 0.82
CG+GG 263 270 0.93 (0.69 – 1.24) 0.61

CC+CG 343 343 1
GG 64 64 1.00 (0.69 – 1.46) 1

OR, odds ratio; CI, confidence interval.

aasOR are adjusted for age and gender.