Table 4.
Non-smoker | Genotype | Cases (n = 108) |
Controls (n = 162) |
OR (95% CI) | p-value | asOR (95% CI)b | p-value |
-3444 C>T | CC | 36 | 61 | 1 | 1 | ||
CT | 48 | 83 | 0.98 (0.57 – 1.69) | 0.94 | 0.99 (0.56 – 1.74) | 0.96 | |
TT | 24 | 18 | 2.26 (1.08 – 4.72) | 0.03 | 2.67 (1.20 – 5.91) | 0.02 | |
CT+TT | 72 | 101 | 1.21 (0.73 – 2.01) | 0.47 | 1.25 (0.73 – 2.14) | 0.41 | |
CC+CT | 84 | 144 | 1 | 1 | |||
TT | 24 | 18 | 2.29 (1.17 – 4.46) | 0.02 | 2.69 (1.30 – 5.56) | 0.01 | |
-1985 G>T | GG | 37 | 61 | 1 | 1 | ||
GT | 47 | 82 | 0.94 (0.55 – 1.63) | 0.84 | 0.97 (0.55 – 1.71) | 0.91 | |
TT | 24 | 19 | 2.08 (1.01 – 4.31) | 0.05 | 2.41 (1.10 – 5.27) | 0.03 | |
GT+TT | 71 | 101 | 1.16 (0.70 – 1.93) | 0.57 | 1.21 (0.71 – 2.07) | 0.48 | |
GG+GT | 84 | 143 | 1 | 1 | |||
TT | 24 | 19 | 2.15 (1.11 – 4.16) | 0.02 | 2.46 (1.20 – 5.01) | 0.01 | |
P1170A C>G | CC | 37 | 58 | 1 | 1 | ||
CG | 48 | 84 | 0.90 (0.52 – 1.54) | 0.69 | 0.89 (0.50 – 1.57) | 0.68 | |
GG | 23 | 20 | 1.80 (0.87 – 3.73) | 0.11 | 2.05 (0.94 – 4.47) | 0.07 | |
CG+GG | 71 | 104 | 1.07 (0.64 – 1.78) | 0.79 | 1.09 (0.64 – 1.86) | 0.76 | |
CC+CG | 85 | 142 | 1 | 1 | |||
GG | 23 | 20 | 1.92 (1.00 – 3.71) | 0.05 | 2.20 (1.08 – 4.47) | 0.03 |
OR, odds ratio; CI, confidence interval.
basOR are adjusted for age and gender.